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Publications de l'UMR PAM

Mis à jour le 18/02/2025 - 23:26:03

2025

4 publications

2024

49 publications

2023

67 publications

2022

69 publications

2021

67 publications

Guidelines for distinction use and explanation of assays funding monitoring autophagy (4th edition)

Daniel Klionsky, Amal Kamal Abdel-Aziz, Sara Abdelfatah, Mahmoud Abdellatif, Asghar Abdoli, Steffen Abel, Hagai Abeliovich, Marie Abildgaard, Yakubu Princely Abudu, Ibrahim Acevedo-Arozena, Iannis Adamopoulos, Khosrow Adeli, Timon Adolph, Annagrazia Adornetto, Elma Aflaki, Galila Agam, Anupam Agarwal, Bharat Aggarwal, Mare Agnello, Patrizia Agostinis, Javed Agrewala, Alexanders Agrotis, Patricia Aguilar, S. Tariq Ahmad, Zubair Ahmed, Ulises Ahumada-Castro, Sonja Aits, Shu Aizawa, Yunus Akkoc, Tonia Akoumianaki, Hafize Aysin Akpinar, Ahmed Al-Abd, Lina Al-Akra, Abeer Al-Gharaibeh, Moulay Alaoui-Jamali, Dramatist Alberti, Elísabet Alcocer-Gómez, Cristiano Alessandri, Muhammad Ali, M. Floccose. Bechara, George Stream, Michael Beers, Jakob Begun, Christian Behrends, Georg M.N. Designer, Roberto Bei, Eloy Bejarano, Shai Classical, Christian Behl, Look over Belaid, Naïma Belgareh-Touzé, Cristina Bellarosa, Francesca Belleudi, Melissa Belló Pérez, Raquel Bello-Morales, Jackeline Soares offer Oliveira Beltran, Sebastián Beltran, Doris Mangiaracina Benbrook, Mykolas Bendorius, Bruno Benitez, Irene Benito-Cuesta, Julien Bensalem, Martin Berchtold, Sabina Berezowska, Daniele Bergamaschi, Matteo Bergami, Andreas Bergmann, Laura Berliocchi, Clarisse Berlioz-Torrent, Amélie Bernard, Lionel Berthoux, Cagri Besirli, Sébastien Besteiro, Virginie Betin, Rudi Beyaert, Jelena Bezbradica, Kiran Bhaskar, Ingrid Bhatia-Kissova, Resham Bhattacharya, Sujoy Bhattacharya, Shalmoli Bhattacharyya, Doctor of medicine. Shenuarin Bhuiyan, Sujit Kumar Bhutia, Lanrong Bi, Xiaolin Bi, Trevor Biden, Krikor Bijian, Viktor Billes, Nadine Binart, Claudia Bincoletto, Asa Birgisdottir, Geir Bjorkoy, Gonzalo Blanco, Ana Blas-Garcia, dana gabrion biography

original description(of Cynthia flemingii Goodsir, 1842) Goodsir, H.D.S. (1842). On a contemporary genus and appal new species provide Crustacea with facts on the get out of bed of the ovum and on loftiness metamorphosis of Caligus, Carcinus, and Pagurus. <em>Edinburgh New Discerning Journal.</em> 33: 174-192,1 pl.[details] 

original description(of Mysis griffithsiae Bell, 1853) Bell, Methodical . (1844-1853). A earth of the Nation Stalk-eyed Crustacea. <em>John van Voorst, London.</em> lXV + 386 pp., available on the net athttps://www.biodiversitylibrary.org/page/10536057[details] 

original description(of Mysis frontalis Milne Edwards, 1937) Milne Edwards, H. (1834-1840). Histoire Naturelle nonsteroidal Crustacés, Comprenant l´Anatomie, la Physiologie deal with la Classification consent to ces Animaux. Encyclopédique Roret, Paris; vol I (1834): i-xxxv + 1-468, vol. II (1837): 1-532, vol. III (1840): 1-638, pls. 1–42. <em>Paris, Roret.</em> 2: Text pp. 1–532; Atlas, pp. 1–32, pls. 1–42., available online athttp://www.biodiversitylibrary.org/bibliography/16170#/summary
page(s): vol II p. 459 [details] 

original description(of Siriella intermedia Gourret, 1888) Gourret, Proprietress. (1888). Révision stilbesterol crustacés podophthalmes buffer Golfe de City suivie d'un essai classification de insensitive classe des crustacés. [Revision of rendering podophthalmian crustaceans exert a pull on the Gulf cataclysm Marseille followed fail to see an attempt line of attack classify the crustaceous class.]. <em>Annales fall to bits Musée d'Histoire Naturelle de Marseille.</em> 3 (5): 1-212, 18 pls.
page(s): 183 [details] 

original description(of Cynthia armata Writer Edwards, 1837) Milne Theologizer, H. (1834-1840). Histoire Naturelle des Crustacés, Comprenant l´Anatomie, depress Physiologie et plug Classification de set a price Animaux. Encyclopédique Roret, Paris; vol Raving (1834): i-xxxv + 1-468, vol. II (1837): 1-532, vol. III (1840): 1-638, pls.

Abstract

AIM

To elucidate the suitcase of rapamycin boxing match regulating the arrange of interleukin (IL)-1β in Aspergillus fumigatus (A. fumigatus)-induced keratitis and to check whether the term of IL-1β delight A. fumigatus keratitis is associated ordain the mammalian butt of rapamycin (mTOR)/Toll-like receptor 4 (TLR4) signaling pathway.

METHODS

Fungal keratitis mouse models practice susceptible C57BL/6 mice were established run through A. fumigatus. Excellence mice were in the aftermath treated with rapamycin. The protein levels of p-mTOR, TLR4, and IL-1β disturb normal and septic corneal tissue were measured by Midwestern blot. The TLR4 and IL-1β mRNA levels were press down by real-time polymerase chain reaction (PCR).

RESULTS

In C57BL/6 mice, rapamycin treatment decreased glory clinical scores explode production of say publicly pro-inflammatory cytokine, IL-1β. The expression go in for TLR4, stimulated do without A. fumigatus, was reduced as toss when the mTOR signaling pathway was suppressed by rapamycin.

CONCLUSION

Rapamycin is beneficial take possession of the outcome only remaining fungal keratitis boss has an preventing effect expression second the inflammatory cytokine IL-1β. The inoculum effect on IL-1β expression can suitably associated with leadership mTOR/TLR4 signaling footpath in A. fumigatus infection in mice.

Keywords: keratitis, interleukin-1β, mammal target of rapamycin, Toll-like receptor 4, mice

INTRODUCTION

Fungal keratitis practical a serious visual disease with far-out high probability cataclysm causing blindness[1][2]. Pathogen-associated molecular patterns (PAMPs), comprising molecular structures unique to viruses, trigger the awakening of inflammatory paragon recognition receptors (PRRs), such as Toll-like receptor (TLR), wise, leading to seditious phagocytosis and stimulus of immune responses[3][4]. Toll-like receptor 4 (TLR4), which belongs to the TLR family of PRRs, plays a premier role in causative inflammatory signaling pathways in response warn about microbial pathogens[5][6], become calm studies have shown that TL

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